It'd be cool, but I really think the DS is too small a screen and too underpowered to port 3D Sam and Max to without sacrificing a few things. Unless the DS game was a whole new game, but I can't see that happening.
Edit: Why do they say LucasArts is the publisher when it looks like they're talking about the new games more than anything?
The DS is a great platform for the type of games we make, but the tech is so different on the DS than on the PC and other consoles. We would have to completely rework our development tools, and that’s not something we’re doing right now. There are a lot of story-driven games coming out for the DS, so that’s encouraging. We’re interested to see how Deck13’s DS port of Ankh turns out because the PC version is pretty similar to our games.
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Edit: Why do they say LucasArts is the publisher when it looks like they're talking about the new games more than anything?
http://www.adventuregamers.com/newsitem.php?id=1407