Unpopular Opinion: I don't expect that many Major Deaths in The Final Episode.
Considering how few Major Deaths have taken place through the course of The Final Season, I feel like it would be somewhat Rushed and Jarring (From a Narrative Perspective) to see more than a couple Major deaths in Episode 4. The reason I say that is because that's the pattern that we've gotten throughout this season so far. Marlon and Brody in Episode 1 is 2 deaths, Both Non-Determinant. Then 1 in Episode 2 (Mitch). Then you have 3 deaths in Episode 3 (Abel, Lilly, and James), but 2 of them are determinant. Whatever choice you make, if you don't include the alternate path, that just leaves 2 deaths for Episode 3.
There are several likely possibilities about who could die in Episode 4. Considering it's been stated previously that determinant characters who don't die in Episode 3 will stay alive in Episode 4, I can most certainly rule out James and Lilly. It could be Clem. It could be AJ. It could even be both depending on your choices. Minerva is another possibility. Kmudle stated on Tumblr (This is how I interpret it) that Minerva is essentially one of those types of people who would rather die than take responsibility for her actions. As I've stated in another thread, I think it's highly likely that Minerva will commit suicide if Tenn finds out what she did to Sophie. Beyond that, I don't see that many major deaths happening in the Finale.